Hospitalization at the end of life in patients with multiple myeloma
dc.contributor.author | Abbasi, Saqib | |
dc.contributor.author | Roller, John | |
dc.contributor.author | Abdallah, Al-Ola | |
dc.contributor.author | Shune, Leyla | |
dc.contributor.author | McClune, Brian | |
dc.contributor.author | Sborov, Douglas | |
dc.contributor.author | Mohyuddin, Ghulam Rehman | |
dc.date.accessioned | 2021-06-23T18:03:13Z | |
dc.date.available | 2021-06-23T18:03:13Z | |
dc.date.issued | 2021-03-31 | |
dc.identifier.citation | Abbasi, S., Roller, J., Abdallah, AO. et al. Hospitalization at the end of life in patients with multiple myeloma. BMC Cancer 21, 339 (2021). https://doi.org/10.1186/s12885-021-08079-x | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/31701 | |
dc.description | A grant from the One-University Open Access Fund at the University of Kansas was used to defray the author's publication fees in this Open Access journal. The Open Access Fund, administered by librarians from the KU, KU Law, and KUMC libraries, is made possible by contributions from the offices of KU Provost, KU Vice Chancellor for Research & Graduate Studies, and KUMC Vice Chancellor for Research. For more information about the Open Access Fund, please see http://library.kumc.edu/authors-fund.xml. | en_US |
dc.description.abstract | Background Despite advances in treatment, multiple myeloma (MM) remains incurable and results in significant morbidity and mortality. Further research investigating where MM patients die and characterization of end-of-life hospitalizations is needed.Methods We utilized the National Inpatient Sample (NIS) to explore the hospitalization burden of MM patients at the end of their lives.Results The percent of patients dying in the hospital as a percent of overall MM deaths ranged from 54% in 2002 to 41.4% in 2017 (p < 0.01). Blood transfusions were received in 32.7% of these hospitalizations and infections were present in 47.8% of patients. Palliative care and/or hospice consultations ranged from 5.3% in 2002 to 31.4% in 2017 (p < 0.01).Conclusion Our study demonstrates that patients with MM dying in the hospital have a significant requirement for blood transfusions and have a high infection burden. We also show that palliative care and hospice involvement at the end of life has increased over time but remains low, and that ultimately, inpatient mortality has decreased over time, but MM patients die in the hospital at a higher rate than the general population. | en_US |
dc.publisher | BMC | en_US |
dc.rights | © The Author(s). 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en_US |
dc.subject | Multiple myeloma | en_US |
dc.subject | Palliative care | en_US |
dc.subject | Hospice | en_US |
dc.subject | Death | en_US |
dc.subject | National inpatient sample | en_US |
dc.subject | Inpatient | en_US |
dc.subject | Hospital | en_US |
dc.title | Hospitalization at the end of life in patients with multiple myeloma | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Abbasi, Saqib | |
kusw.kuauthor | Roller, John | |
kusw.kuauthor | Abdallah, Al-Ola | |
kusw.kuauthor | Shune, Leyla | |
kusw.kuauthor | Mohyuddin, Ghulam Rehman | |
kusw.kudepartment | KU Medical Center | en_US |
dc.identifier.doi | 10.1186/s12885-021-08079-x | en_US |
kusw.oaversion | Scholarly/refereed, publisher version | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.rights.accessrights | openAccess | en_US |
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Except where otherwise noted, this item's license is described as: © The Author(s). 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.