dc.contributor.author | Robinson, Jennifer L. | |
dc.contributor.author | Johnson, Pamela M. | |
dc.contributor.author | Kister, Karolina | |
dc.contributor.author | Yin, Michael T. | |
dc.contributor.author | Chen, Jing | |
dc.contributor.author | Wadhwa, Sunil | |
dc.date.accessioned | 2020-06-18T21:05:53Z | |
dc.date.available | 2020-06-18T21:05:53Z | |
dc.date.issued | 2020-04-30 | |
dc.identifier.citation | Robinson, J. L., Johnson, P. M., Kister, K., Yin, M. T., Chen, J., & Wadhwa, S. (2020). Estrogen signaling impacts temporomandibular joint and periodontal disease pathology. Odontology, 108(2), 153–165. https://doi.org/10.1007/s10266-019-00439-1 | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/30556 | |
dc.description | This work is licensed under a Creative Commons Attribution 4.0 International License. | en_US |
dc.description.abstract | Women experience a higher incidence of oral diseases including periodontal diseases and temporomandibular joint disease (TMD) implicating the role of estrogen signaling in disease pathology. Fluctuating levels of estrogen during childbearing age potentiates facial pain, high estrogen levels during pregnancy promote gingivitis, and low levels of estrogen during menopause predisposes the TMJ to degeneration and increases alveolar bone loss. In this review, an overview of estrogen signaling pathways in vitro and in vivo that regulate pregnancy-related gingivitis, TMJ homeostasis, and alveolar bone remodeling is provided. Deciphering the specific estrogen signaling pathways for individual oral diseases is crucial for potential new drug therapies to promote and maintain healthy tissue. | en_US |
dc.publisher | Springer Verlag | en_US |
dc.rights | © 2019, Springer Nature. | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en_US |
dc.subject | Estrogen | en_US |
dc.subject | Temporomandibular joint | en_US |
dc.subject | Periodontal disease | en_US |
dc.subject | Alveolar bone | en_US |
dc.subject | Oral health | en_US |
dc.subject | Women’s health | en_US |
dc.title | Estrogen signaling impacts temporomandibular joint and periodontal disease pathology | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Robinson, Jennifer L. | |
kusw.kuauthor | Johnson, Pamela M. | |
kusw.kudepartment | Chemical and Petroleum Engineering | en_US |
kusw.kudepartment | Bioengineering Graduate Program | en_US |
kusw.oanotes | Per SHERPA/RoMEO 6/18/2020:Journal: Odontology (ISSN: 1618-1247, ESSN: 1618-1255)
RoMEO: This is a RoMEO green journal
Paid OA: A paid open access option is available for this journal.
Author's Pre-print: green tick author can archive pre-print (ie pre-refereeing)
Author's Post-print: green tick author can archive post-print (ie final draft post-refereeing)
Publisher's Version/PDF: cross author cannot archive publisher's version/PDF
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Author's pre-print on pre-print servers such as arXiv.org
Author's post-print on author's personal website immediately
Author's post-print on any open access repository after 12 months after publication
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dc.identifier.doi | 10.1007/s10266-019-00439-1 | en_US |
kusw.oaversion | Scholarly/refereed, author accepted manuscript | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.identifier.pmid | PMC7192637 | en_US |
dc.rights.accessrights | openAccess | en_US |