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dc.contributor.authorRobinson, Jennifer L.
dc.contributor.authorJohnson, Pamela M.
dc.contributor.authorKister, Karolina
dc.contributor.authorYin, Michael T.
dc.contributor.authorChen, Jing
dc.contributor.authorWadhwa, Sunil
dc.identifier.citationRobinson, J. L., Johnson, P. M., Kister, K., Yin, M. T., Chen, J., & Wadhwa, S. (2020). Estrogen signaling impacts temporomandibular joint and periodontal disease pathology. Odontology, 108(2), 153–165.
dc.descriptionThis work is licensed under a Creative Commons Attribution 4.0 International License.en_US
dc.description.abstractWomen experience a higher incidence of oral diseases including periodontal diseases and temporomandibular joint disease (TMD) implicating the role of estrogen signaling in disease pathology. Fluctuating levels of estrogen during childbearing age potentiates facial pain, high estrogen levels during pregnancy promote gingivitis, and low levels of estrogen during menopause predisposes the TMJ to degeneration and increases alveolar bone loss. In this review, an overview of estrogen signaling pathways in vitro and in vivo that regulate pregnancy-related gingivitis, TMJ homeostasis, and alveolar bone remodeling is provided. Deciphering the specific estrogen signaling pathways for individual oral diseases is crucial for potential new drug therapies to promote and maintain healthy tissue.en_US
dc.publisherSpringer Verlagen_US
dc.rights© 2019, Springer Nature.en_US
dc.subjectTemporomandibular jointen_US
dc.subjectPeriodontal diseaseen_US
dc.subjectAlveolar boneen_US
dc.subjectOral healthen_US
dc.subjectWomen’s healthen_US
dc.titleEstrogen signaling impacts temporomandibular joint and periodontal disease pathologyen_US
kusw.kuauthorRobinson, Jennifer L.
kusw.kuauthorJohnson, Pamela M.
kusw.kudepartmentChemical and Petroleum Engineeringen_US
kusw.kudepartmentBioengineering Graduate Programen_US
kusw.oanotesPer SHERPA/RoMEO 6/18/2020:

Journal: Odontology (ISSN: 1618-1247, ESSN: 1618-1255) RoMEO: This is a RoMEO green journal Paid OA: A paid open access option is available for this journal. Author's Pre-print: green tick author can archive pre-print (ie pre-refereeing) Author's Post-print: green tick author can archive post-print (ie final draft post-refereeing) Publisher's Version/PDF: cross author cannot archive publisher's version/PDF General Conditions: Author's pre-print on pre-print servers such as Author's post-print on author's personal website immediately Author's post-print on any open access repository after 12 months after publication Publisher's version/PDF cannot be used Published source must be acknowledged Must link to publisher version Set phrase to accompany link to published version (see policy) Articles in some journals can be made Open Access on payment of additional charge
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US

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© 2019, Springer Nature.
Except where otherwise noted, this item's license is described as: © 2019, Springer Nature.