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    Deciphering the role of substrate stiffness to enhance internalization efficiency of plasmid DNA in stem cells using lipid-based nanocarriers

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    Issue Date
    2018-04-06
    Author
    Modaresi, Saman
    Pacelli, Settimio
    Whitlow, Jonathan
    Paul, Arghya
    Publisher
    Royal Society of Chemistry
    Type
    Article
    Article Version
    Scholarly/refereed, author accepted manuscript
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    Abstract
    This study investigates the role of substrate stiffness on non-viral transfection of human adipose-derived stem cells (hASCs) with the aim to maximize hASCs expression of vascular endothelial growth factor (VEGF). The results confirm the direct effect of substrate stiffness in regulating cytoskeletal remodeling and corresponding plasmid internalization.
    URI
    http://hdl.handle.net/1808/26458
    DOI
    https://doi.org/10.1039/C8NR01516C
    Collections
    • Chemical & Petroleum Engineering Scholarly Works [173]
    Citation
    Modaresi, S., Pacelli, S., Whitlow, J., & Paul, A. (2018). Deciphering the role of substrate stiffness to enhance internalization efficiency of plasmid DNA in stem cells using lipid-based nanocarriers. Nanoscale, 10(19), 8947–8952. http://doi.org/10.1039/c8nr01516c

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    KU Libraries
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    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
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    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

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