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    First Report of Leishmania tropica from a Classical Focus of L. major in North-Sinai, Egypt

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    Shehata_et_al_2009.pdf (565.9Kb)
    Issue Date
    2009-08-01
    Author
    Shehata, Magdi G.
    Samy, Abdallah M.
    Doha, Said Abdallah
    Fahmy, Adel R.
    Kaldas, Rania M.
    Furman, Barry D.
    Villinski, Jeffrey T.
    Publisher
    American Society of Tropical Medicine and Hygiene
    Type
    Article
    Article Version
    Scholarly/refereed, publisher version
    Published Version
    http://www.ajtmh.org/content/81/2/213.long
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    Abstract
    Cutaneous leishmaniasis (CL) is prevalent in the Egyptian Sinai Peninsula and previous research has consistently documented the etiologic agent to be Leishmania major. We report the first isolation of Leishmania tropica from human cases of CL in a Northern Sinai community bordering Palestine. Parasite culturing, real-time polymerase chain reaction (PCR), gene sequencing, and restriction fragment length polymorphism (RFLP) analyses indicate CL cases in this community were caused by either L. major or L. tropica (three cases each). Two wild-caught rodents (Gerbillus pyramidum floweri) were infected with L. tropica. Phlebotomus papatasi sand flies were found harboring L. major, however only non-infected individuals of Phlebotomus sergenti, a vector for L. tropica, were caught. Patients with L. tropica had not traveled from the region in over a year, suggesting these cases are autochthonous. This scenario is consistent with an incursion of L. tropica from bordering countries and raises concerns about expansion of this parasite further into Egypt.
    Description
    This is the publisher's version, also available electronically from http://www.ajtmh.org/content/81/2/213.long.
    URI
    http://hdl.handle.net/1808/15181
    Collections
    • Ecology & Evolutionary Biology Scholarly Works [1516]
    Citation
    Shehata, Magdi G. et al. (2009). "First Report of Leishmania tropica from a Classical Focus of L. major in North-Sinai, Egypt." Am J Trop Med Hyg, 81(2):213. http://www.ajtmh.org/content/81/2/213.long

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    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

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