Molecular Biosciences Dissertations and Theses: Recent submissions
Now showing items 21-40 of 270
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exc-2, an intermediate filament gene, maintains tubular excretory canals in Caenorhabditis elegans along with ifa-4 and other novel genes.
(University of Kansas, 2018-05-31)The excretory canals of Caenorhabditis elegans are a model for understanding the maintenance of apical morphology in narrow single-celled tubes. Light and electron microscopy shows that mutants in exc-2 start to form canals ... -
A study of rennin action
(University of Kansas, 1927) -
Studies on isohemagglutination
(University of Kansas, 1929) -
The Activity of Phosphorylase Kinase Revisited
(University of Kansas, 2018-05-31)Phosphorylase Kinase (PhK) is an essential regulatory enzyme in the glycogenolysis cascade. PhK is a large, 16-subunit enzyme complex with the subunit stoichiometry (alpha-beta-gamma-delta)4, and is subject to extensive ... -
Modeling the in vitro aggregation of 4R tau isoforms for a comparative study of FTDP-17 mutants
(University of Kansas, 2017-12-31)Tau is a microtubule binding protein typically found in neuronal axons. In an adult human brain, six isoforms of tau are generated by alternate mRNA splicing. These isoforms of tau differ from each other either based on ... -
O-GlcNAc Regulation of Mitochondrial Function and Energy Metabolism
(University of Kansas, 2017-05-31)O-GlcNAc is a post-translational modification (PTM) of a single N-acetylglucosamine sugar attachment on serine or threonine residues of nuclear, cytoplasmic, and mitochondrial proteins. Two opposing enzymes facilitate the ... -
Studies in experimental anaphylaxis
(University of Kansas, 1929) -
Immunological studies on Bacterium tularense
(University of Kansas, 1950) -
Experimental investigations on the respiration and pathogenesis of typhus fever rickettsiae
(University of Kansas, 1950) -
Immunogenic properties for the white mouse of various strains of Bacterium tularense
(University of Kansas, 1949) -
DISCOVERY OF GENETIC CORRELATES IMPORTANT FOR CHLAMYDIA INFECTION AND PATHOGENESIS
(University of Kansas, 2017-08-31)Chlamydia species are responsible for over 1.2 million reports of bacterial sexually transmitted infections in the United States; a number that has been steadily increasing for the past decade. Worldwide, a cumulative 131 ... -
Application of RAD-seq in Evolutionary Genomics of Non-Model Organisms
(University of Kansas, 2017-05-31)Next generation sequencing (NGS) technologies are revolutionizing how we study genetics and evolution in the modern world. Data is generated at such a fast pace that scientists are struggling to keep up with the innovations ... -
Studies on the nutrition of Clostridium welchii in relation to toxin production
(University of Kansas, 1941) -
Studies on natural immunity in the cat
(University of Kansas, 1940) -
A Framework for Studying Crucial Steps in Proteasome Core Particle Assembly
(University of Kansas, 2017-08-31)The ability of proteins to repeatedly and reliably self-assemble in the cell is a critical element of the maintenance of life. Despite this, the mechanisms that underlie these events are poorly understood. The proteasome ... -
Biophysical studies of the Burkholderia minor translocon protein BipC by NMR and CD spectroscopy
(University of Kansas, 2017-05-31)Abstract The type III secretion system (T3SS) provides many Gram-negative pathogens a tool to initiate, maintain and proliferate infection in the host. The T3SS is a syringe-like apparatus composed of a base that transverses ... -
O-GlcNAc Regulates Erythroid Gene Transcription
(University of Kansas, 2017-08-31)O-GlcNAc is a post-translational modification on serine or threonine residues by β-N-acetylglucosamine. O-GlcNAc is added and removed from serine and threonine residues by the O-GlcNAc processing enzymes, O-GlcNAc-transferase ... -
Taxotere suppresses breast cancer growth through inducing lincRNA-p21 expression
(University of Kansas, 2017-05-31)It has been reported that long non-coding RNA lincRNA-p21 is induced upon radiation and chemotherapy. This induction contributes to DNA-damage repair, cell death and cell cycle regulation. In this study, we focused on ... -
Identifying cellular kinases that regulate HSV-1 ICP0 activities and viral replication.
(University of Kansas, 2016-12-31)Herpes simplex virus 1 (HSV-1) infects a significant number of people worldwide and is the number one cause of infectious blindness in western industrialized countries. HSV-1 causes a lifelong latent infection that can be ...