dc.contributor.author | Shinde, Anand H. | |
dc.contributor.author | Nagamalla, Someshwar | |
dc.contributor.author | Sathyamoorthi, Shyam | |
dc.date.accessioned | 2023-06-13T15:38:56Z | |
dc.date.available | 2023-06-13T15:38:56Z | |
dc.date.issued | 2020-05-17 | |
dc.identifier.citation | Shinde, A.H., Nagamalla, S. & Sathyamoorthi, S. N-arylated oxathiazinane heterocycles are convenient synthons for 1,3-amino ethers and 1,3-amino thioethers. Med Chem Res 29, 1223–1229 (2020). https://doi.org/10.1007/s00044-020-02556-x | en_US |
dc.identifier.uri | https://hdl.handle.net/1808/34348 | |
dc.description.abstract | This communication describes a variety of nucleophilic ring openings of N-arylated oxathiazinane heterocycles. We find that this reaction is compatible with phenoxides, naphthoxides, and thiolates and allows for the rapid assembly of N-aryl-amino ethers and N-aryl-amino thioethers. Fourteen examples are shown and a mechanistic pathway is hypothesized. | en_US |
dc.publisher | Springer | en_US |
dc.rights | Copyright © 2020, Springer Science Business Media, LLC, part of Springer Nature. | en_US |
dc.subject | Nucleophile | en_US |
dc.subject | Sulfamate | en_US |
dc.subject | Oxathiazinane | en_US |
dc.subject | Aza-Wacker | en_US |
dc.title | N-arylated oxathiazinane heterocycles are convenient synthons for 1,3-amino ethers and 1,3-amino thioethers | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Shinde, Anand H. | |
kusw.kuauthor | Nagamalla, Someshwar | |
kusw.kuauthor | Sathyamoorthi, Shyam | |
kusw.kudepartment | Medicinal Chemistry | en_US |
dc.identifier.doi | 10.1007/s00044-020-02556-x | en_US |
dc.identifier.orcid | https://orcid.org/0000-0003-4705-7349 | en_US |
kusw.oaversion | Scholarly/refereed, author accepted manuscript | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.identifier.pmid | PMC10191371 | en_US |
dc.rights.accessrights | openAccess | en_US |