University of Kansas Medical Center Scholarly Works
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Oculomotor Deficits and Symptom Severity Are Associated With Poorer Dynamic Mobility in Chronic Mild Traumatic Brain Injury
(Frontiers Media, 2021-07-26)Oculomotor deficits, vestibular impairments, and persistent symptoms are common after a mild traumatic brain injury (mTBI); however, the relationship between visual-vestibular deficits, symptom severity, and dynamic mobility ... -
Infection risks in multiple myeloma: A systematic review and meta-analysis of randomized trials from 2015 to 2019
(BMC, 2021-06-26)Background Patients with multiple myeloma (MM) remain at an increased risk of infection due to the disease process, as well as the ensuing treatments. Methods We performed a systematic review to evaluate the monthly ... -
Differences in Outcomes Between Anterior and Posterior Shoulder Instability After Arthroscopic Bankart Repair: A Systematic Review and Meta-analysis
(SAGE Publications, 2021-05-25)Background: The glenohumeral joint is one of the most frequently dislocated joints in the body, particularly in young, active adults. Purpose: To conduct a systematic review and meta-analysis to evaluate and compare ... -
Hospitalization at the end of life in patients with multiple myeloma
(BMC, 2021-03-31)Background Despite advances in treatment, multiple myeloma (MM) remains incurable and results in significant morbidity and mortality. Further research investigating where MM patients die and characterization of end-of-life ... -
Imaging Modalities for the Glenoid Track in Recurrent Shoulder Instability: A Systematic Review
(SAGE Publications, 2021-06-01)Background: The glenoid track (GT) concept illustrates how the degree of glenoid bone loss and humeral bone loss in the glenohumeral joint can guide further treatment in a patient with anterior instability. The importance ... -
Genomic, Clinical, and Behavioral Characterization of 15q11.2 BP1-BP2 Deletion (Burnside-Butler) Syndrome in Five Families
(MDPI, 2021-02-07)The 15q11.2 BP1-BP2 deletion (Burnside-Butler) syndrome is emerging as the most common cytogenetic finding in patients with neurodevelopmental or autism spectrum disorders (ASD) presenting for microarray genetic testing. ... -
Association between Primary Perioperative CEA Ratio, Tumor Site, and Overall Survival in Patients with Colorectal Cancer
(MDPI, 2020-11-27)There are differences in the incidence, clinical presentation, molecular pathogenesis, and outcome of colorectal cancer (CRC) based on tumor location. Emerging research suggests that the perioperative carcinoembryonic ... -
Outcomes of intraoperative ultrasound for endoscopic endonasal transsphenoidal pituitary surgery in adenomas with parasellar extension
(Elsevier, 2021-04-18)Background Pituitary adenomas with parasellar extension present a technical challenge for adequate visualization and gross total resection (GTR). The endoscope improves identification of parasellar extension, however, ... -
Association of Neutrophil, Platelet, and Lymphocyte Ratios with the Prognosis in Unresectable and Metastatic Pancreatic Cancer
(MDPI, 2020-10-13)We examined the relationship between the daily rate of change of cancer antigen 19-9 (CA19-9) over the first 90 days of treatment (DRC90) and the pretreatment levels of neutrophils, lymphocytes, and platelets with the ... -
Survival Outcomes of Pancreatic Intraepithelial Neoplasm (PanIN) versus Intraductal Papillary Mucinous Neoplasm (IPMN) Associated Pancreatic Adenocarcinoma
(MDPI, 2020-09-25)Pancreatic intraepithelial neoplasms (PanINs) and intraductal papillary mucinous neoplasms (IPMNs) are common pancreatic adenocarcinoma precursor lesions. However, data regarding their respective associations with survival ... -
The Ketogenic Diet in the Treatment of Post-concussion Syndrome—A Feasibility Study
(Frontiers Media, 2020-09-10)Concussion is the most common form of mild traumatic brain injury (mTBI). Although most patients' symptoms resolve within a month, patients with post-concussion syndrome (PCS) may continue to experience symptoms for years ... -
Association of Current Opioid Use With Serious Adverse Events Among Older Adult Survivors of Breast Cancer
(JAMA Network, 2020-09-15)Importance National efforts to improve safe opioid prescribing focus on preventing misuse, overdose, and opioid use disorder. This approach overlooks opportunities to better prevent other serious opioid-related harms in ... -
Investigating the relationship between individual differences and island sensitivity
(Ubiquity Press, 2020-09-17)It is well-attested that native speakers tend to give low acceptability ratings to sentences that involve movement from within islands, yet the source of island effects remains an active debate. The grammatical account ... -
Notch4 activation aggravates NF-κB-mediated inflammation in HIV-1-associated nephropathy
(The Company of Biologists, 2019-12-17)Notch pathway activation plays a central role in the pathogenesis of many glomerular diseases. We have previously shown that Notch4 expression was upregulated in various renal cells in human immunodeficiency virus ... -
“It’s like heaven over there”: Medicine as discipline and the production of the carceral body
(BMC, 2020-02-08)Background Correctional systems in several U.S. states have entered into partnerships with Academic Medical Centers (AMCs) to provide healthcare for people who are incarcerated. This project was initiated to better ... -
Middle cerebral artery velocity dynamic response profile during exercise is attenuated following multiple ischemic strokes: A case report
(Physiological Society, 2019-11-05)Blood flow regulation is impaired in people with stroke. However, the time course of change in middle cerebral artery velocity (MCAv) following repeated stroke at rest and during exercise remains unknown. In this case ... -
Unremitting chronic skin lesions: A case of delayed diagnosis of glucagonoma
(Taylor & Francis Open Access, 2019-11-01)A 54-year-old Caucasian male with history of hypertension, hyperlipidemia, insulin-dependent diabetes mellitus, and chronic skin rash of 4 years presented to the emergency department with worsening rash and weight loss. ... -
Metabolomic Profiling to Identify Molecular Biomarkers of Cellular Response to Methotrexate In Vitro
(Wiley Open Access, 2019-10-25)Variation in methotrexate (MTX) efficacy represents a significant barrier to early and effective disease control in the treatment of autoimmune arthritis. We hypothesize that the utilization of metabolomic techniques will ... -
Effect of Cognitive Behavioral Therapy for Insomnia on Insomnia Symptoms for Individuals With Type 2 Diabetes: Protocol for a Pilot Randomized Controlled Trial
(JMIR Publications, 2019-11-12)Background: Insomnia symptoms are a common form of sleep difficulty among people with type 2 diabetes (T2D) affecting sleep quality and health outcomes. Several interventional approaches have been used to improve sleep ... -
Perception, knowledge, and interest of urologic surgery: A medical student survey
(BMC, 2019-09-13)Background Although only a limited number of medical schools require a formal educational rotation in urologic surgery, urology as a medical specialty continues to attract a large number of students into the match each ...