Fischer, Kenneth JVarre, Mathew Sunil2011-11-132011-11-132011-09-082011http://dissertations.umi.com/ku:11740https://hdl.handle.net/1808/8380The distal radioulnar joint (DRUJ) is a joint of the wrist which allows force transmission and forearm rotation in the upper limb while preserving the stability of the forearm independent of elbow and wrist flexion and extension. DRUJ is a commonly injured part of the body. Conditions affecting the joint could be positive ulnar variance or negative ulnar variance, the length of the ulna relative to radius. It is also adversely affected by nearby injuries such as distal radial fractures. In fact, a significant correlation was found between negative ulnar variance and scapholunate dissociation (SLD), a ligament injury of the wrist. This leads to the question of whether or not SLD causes changes in the radioulnar joint mechanics. Altered joint mechanics are associated with the onset of osteoarthritis (OA). An understanding of the of the normal and pathological wrist in vivo DRUJ contact mechanics should help physicians make better clinical recommendations and improve treatment for the primary injury. Proper treatment of the DRUJ could help prevent the onset of OA. Image registration is used in our modeling to determine the kinematic transformations for carpal bones from the unloaded to the loaded configuration. A perturbation study was done to evaluate the effect of varying initial manual registrations and the relative image plane orientations on the final registration kinematics. The results of the study showed that Subject II (with different imaging plane orientations) was found to have greater translation errors compared to subject I (consistent imaging planes). This result emphasizes the need to be consistent with forearm position and/or image plane orientation to minimize the errors of translation and attitude vectors. In a separate study, five additional subjects with unilateral SLD participated in another study in which MRI based contact modeling was used to analyze the contact mechanics parameters of the injured wrist compared to the normal wrist. The contact forces, peak contact pressures, average pressures and contact areas generally trended to be higher in injured wrists compared to the normal and surgically repaired wrists. Model contact areas were found to be consistent with the directly measured areas from the grasp MR images. A repeatability test was done on a single subject and the absolute differences between the contact parameters for both the trials were close. These findings suggest that SLD injury of the wrist may have an effect on the DRUJ mechanics.86 pagesenThis item is protected by copyright and unless otherwise specified the copyright of this thesis/dissertation is held by the author.Mechanical engineeringBiomechanicsDistal radioulnar jointIni vivo contact mechanicsMri based contact modelingWrist mechanicsThesisopenAccess