Tong, XiaoqinZhang, HuapingTimmermann, Barbara N.2017-05-082017-05-082011-12Tong, Xiaoqin, Huaping Zhang, and Barbara N. Timmermann. “Chlorinated Withanolides from Withania Somnifera.” Phytochemistry letters 4.4 (2011): 411–414.https://hdl.handle.net/1808/24028A chlorinated withanolide, 6α-chloro-5β,17α-dihydroxywithaferin A (1), and nine known withanolides, 6α-chloro-5β-hydroxywithaferin A (2), (22R)-5β-formyl-6β,27-dihydroxy-1-oxo-4-norwith-24-enolide, withaferin A, 2,3-dihydrowithaferin A, 3-methoxy-2,3-dihydrowithaferin A, 2,3-didehydrosomnifericin, withanone, withanoside IV and withanoside X, were isolated from Withania somnifera (Solanaceae). All structures were elucidated on the basis of spectroscopic methods (IR, HRESIMS, 1D/2D NMR). X-ray crystallography confirmed the absolute configuration of 1.This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 3.0 (CC BY-NC-ND 3.0 US), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.http://creativecommons.org/licenses/by-nc-nd/3.0/Chlorinated withanolideWithania somniferaSolanaceaeNMRCrystal structureArticle10.1016/j.phytol.2011.04.016PMC3223914openAccess