Synthesis of Chiral Nonracemic Tertiary α-Thio and α-Sulfonyl Acetic Esters via SN2 Reactions of Tertiary Mesylates

Weaver, Jimmie D.Morris, David K.Tunge, Jon A.2017-01-052017-01-052009-09-08Tunge, Jon, Jimmie Weaver, and David Morris. "Synthesis of Chiral Nonracemic Tertiary Î±-Thio and Î±-Sulfonyl Acetic Esters via SN2 Reactions of Tertiary Mesylates." Synlett 2010.03 (2010): 470-74.https://hdl.handle.net/1808/22458Syntheses of enantioenriched sulfides and sulfones via substitution of tertiary mesylate with thiolate nucleophile were achieved with modest to excellent success.SulfideSulfoneSn2 reactionSynthesis of Chiral Nonracemic Tertiary α-Thio and α-Sulfonyl Acetic Esters via SN2 Reactions of Tertiary MesylatesArticle10.1055/s-0029-1219186openAccess