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dc.contributor.advisorCarlson, Susan
dc.contributor.authorKreber, Nicole Lynn
dc.date.accessioned2010-03-18T04:43:12Z
dc.date.available2010-03-18T04:43:12Z
dc.date.issued2009-12-11
dc.date.submitted2009
dc.identifier.otherhttp://dissertations.umi.com/ku:10644
dc.identifier.urihttp://hdl.handle.net/1808/5981
dc.description.abstractDocosahexaenoic acid (DHA) is a long-chain fatty acid essential for brain growth and cognitive development in infancy. There is some evidence that DHA can also influence growth in infancy and early childhood. Several clinical trials with infants and young children have found lower normalized growth following DHA increased exposure through maternal supplementation during pregnancy and/or lactation or infant formula supplementation. The aim of this study was to evaluate the impact of feeding one of four concentrations of DHA in infant formula on weight-for-length percentile ( or =2 years) at twelve study visits from birth to four years of age. Healthy formula-fed infants were randomized to one of four infant formulas containing 0, 0.32, 0.64, or 0.96% of total fatty acid from DHA. Weight, length, and head circumference were measured at 6 weeks, 4 months, 6 months, 9 months, 12 months, 18 months, 2 years, 2.5 years, 3 years, 3.5 years, and 4 years of age. Subjects were normalized to the Center for Disease Control weight-for-length ( or =2 years) by calculating percentiles. The relationship between weight-for-length and BMI-age percentiles across study visits and DHA concentration in the study formula were evaluated with a two way repeated measures ANOVA using a p-value of 0.05 as statistically significant. The concentration of DHA consumed through infant formula during the first year of life did not impact weight-for-length or BMI-age percentile from birth to 4 years of age (P =0.683). When grouped by DHA or no DHA there was no statistical significance (P =0.416). There is no observable difference in weight-for-length or BMI-age in infants supplemented DHA through infant formula in the first four years of life.
dc.format.extent92 pages
dc.language.isoEN
dc.publisherUniversity of Kansas
dc.rightsThis item is protected by copyright and unless otherwise specified the copyright of this thesis/dissertation is held by the author.
dc.subjectHealth sciences
dc.subjectNutrition
dc.subjectAge
dc.subjectDocosahexaenoic acid
dc.subjectGrowth
dc.subjectObesity
dc.subjectOverweight
dc.subjectSmoking
dc.titleInfant Formula Docosahexaenoic Acid and Body Mass Index to Four Years of Age
dc.typeThesis
dc.contributor.cmtememberGriffith, Linda
dc.contributor.cmtememberGoetz, Jeannine
dc.contributor.cmtememberKingsley, David
dc.thesis.degreeDisciplineDietetics & Nutrition
dc.thesis.degreeLevelM.S.
kusw.oastatusna
kusw.oapolicyThis item does not meet KU Open Access policy criteria.
dc.rights.accessrightsopenAccess


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