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dc.contributor.authorCosgrove, Kelly T.
dc.contributor.authorMcDermott, Timothy J.
dc.contributor.authorWhite, Evan J.
dc.contributor.authorMosconi, Matthew W.
dc.contributor.authorThompson, Wesley K.
dc.contributor.authorPaulus, Martin P.
dc.contributor.authorCardenas-Iniguez, Carlos
dc.contributor.authorAupperle, Robin L.
dc.identifier.citationCosgrove, K.T., McDermott, T.J., White, E.J. et al. Limits to the generalizability of resting-state functional magnetic resonance imaging studies of youth: An examination of ABCD Study® baseline data. Brain Imaging and Behavior 16, 1919–1925 (2022).
dc.description.abstractThis study examined how resting-state functional magnetic resonance imaging (rs-fMRI) data quality and availability relate to clinical and sociodemographic variables within the Adolescent Brain Cognitive Development Study. A sample of participants with an adequate sample of quality baseline rs-fMRI data containing low average motion (framewise displacement ≤ 0.15; low-noise; n = 4,356) was compared to a sample of participants without an adequate sample of quality data and/or containing high average motion (higher-noise; n = 7,437) using Chi-squared analyses and t-tests. A linear mixed model examined relationships between clinical and sociodemographic characteristics and average head motion in the sample with low-noise data. Relative to the sample with higher-noise data, the low-noise sample included more females, youth identified by parents as non-Hispanic white, and youth with married parents, higher parent education, and greater household incomes (ORs = 1.32–1.42). Youth in the low-noise sample were also older and had higher neurocognitive skills, lower BMIs, and fewer externalizing and neurodevelopmental problems (ds = 0.12–0.30). Within the low-noise sample, several clinical and demographic characteristics related to motion. Thus, participants with low-noise rs-fMRI data may be less representative of the general population and motion may remain a confound in this sample. Future rs-fMRI studies of youth should consider these limitations in the design and analysis stages in order to optimize the representativeness and clinical relevance of analyses and results.en_US
dc.rightsCopyright © 2022, The Author(s), under exclusive licence to Springer Science Business Media, LLC, part of Springer Natureen_US
dc.subjectABCD Studyen_US
dc.subjectResting-state fMRIen_US
dc.subjectHead motionen_US
dc.subjectSociodemographic factorsen_US
dc.titleLimits to the generalizability of resting-state functional magnetic resonance imaging studies of youth: An examination of ABCD Study® baseline dataen_US
kusw.kuauthorMosconi, Matthew W.
kusw.kudepartmentKansas Center for Autism Research and Trainingen_US
kusw.oanotesPer Sherpa Romeo 08/15/2022:

Brain Imaging and Behavior [Open panel below]Publication Information TitleBrain Imaging and Behavior [English] ISSNs Print: 1931-7557 Electronic: 1931-7565 URL PublishersSpringer [Commercial Publisher] TJ Status Plan S Approved Jisc Approved [Open panel below]Publisher Policy Open Access pathways permitted by this journal's policy are listed below by article version. Click on a pathway for a more detailed view.

Published Version NoneCC BYPMC Any Website, Journal Website, +3 Accepted Version [pathway a]

None Author's Homepage Accepted Version [pathway b]

12mPublisher's Bespoke License Institutional Repository, Funder Designated Location Embargo12 Months LicencePublisher's Bespoke License Location Funder Designated Location Institutional Repository Conditions Published source must be acknowledged Must link to publisher version with DOI Post-prints are subject to Springer Nature re-use terms
kusw.oaversionScholarly/refereed, publisher versionen_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US

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