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Electrophilically Activated Nitroalkanes in Synthesis of 3,4-Dihydroquinozalines

dc.contributor.authorAksenov, Alexander V.
dc.contributor.authorGrishin, Igor Yu.
dc.contributor.authorAksenov, Nicolai A.
dc.contributor.authorMalyuga, Vladimir V.
dc.contributor.authorAksenov, Dmitrii A.
dc.contributor.authorNobi, Mezvah A.
dc.contributor.authorRubin, Michael
dc.date.accessioned2021-12-06T22:53:59Z
dc.date.available2021-12-06T22:53:59Z
dc.date.issued2021-07-14
dc.identifier.citationAksenov, A.V.; Grishin, I.Y.; Aksenov, N.A.; Malyuga, V.V.; Aksenov, D.A.; Nobi, M.A.; Rubin, M. Electrophilically Activated Nitroalkanes in Synthesis of 3,4-Dihydroquinozalines. Molecules 2021, 26, 4274. https://doi.org/10.3390/molecules26144274en_US
dc.identifier.urihttp://hdl.handle.net/1808/32264
dc.description.abstractNitroalkanes activated with polyphosphoric acid serve as efficient electrophiles in reactions with various nucleophilic amines. Strategically placed second functionality allows for the design of annulation reactions enabling preparation of various heterocycles. This strategy was employed to develop an innovative synthetic approach towards 3,4-dihydroquinazolines from readily available 2-(aminomethyl)anilines.en_US
dc.publisherMDPIen_US
dc.rights© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.en_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.subjectNitroalkanesen_US
dc.subjectHeterocyclic compoundsen_US
dc.subjectQuinozalinesen_US
dc.subjectAnnulationen_US
dc.titleElectrophilically Activated Nitroalkanes in Synthesis of 3,4-Dihydroquinozalinesen_US
dc.typeArticleen_US
kusw.kuauthorNobi, Mezvah A.
kusw.kuauthorRubin, Michael
kusw.kudepartmentChemistryen_US
dc.identifier.doi10.3390/molecules26144274en_US
dc.identifier.orcidhttps://orcid.org/ 0000-0002-6644-9949en_US
dc.identifier.orcidhttps://orcid.org/ 0000-0003-4261-824Xen_US
dc.identifier.orcidhttps://orcid.org/ 0000-0002-7125-9066en_US
kusw.oaversionScholarly/refereed, publisher versionen_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.identifier.pmidPMC8306411en_US
dc.rights.accessrightsopenAccessen_US


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© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
Except where otherwise noted, this item's license is described as: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.