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dc.contributor.authorHamilton, Kristen R.
dc.contributor.authorSmith, Jason F.
dc.contributor.authorGonçalves, Stefanie F.
dc.contributor.authorNketia, Jazlyn A.
dc.contributor.authorTasheuras, Olivia N.
dc.contributor.authorYoon, Mark
dc.contributor.authorRubia, Katya
dc.contributor.authorChirles, Theresa J.
dc.contributor.authorLejuez, Carl W.
dc.contributor.authorShackman, Alexander J.
dc.identifier.citationHamilton, K. R., Smith, J. F., Gonçalves, S. F., Nketia, J. A., Tasheuras, O. N., Yoon, M., Rubia, K., Chirles, T. J., Lejuez, C. W., & Shackman, A. J. (2020). Striatal bases of temporal discounting in early adolescents. Neuropsychologia, 144, 107492.
dc.descriptionThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.en_US
dc.description.abstractSteeper rates of temporal discounting—the degree to which smaller-sooner (SS) rewards are preferred over larger-later (LL) ones—have been associated with impulsive and ill-advised behaviors in adolescence. Yet, the underlying neural systems remain poorly understood. Here we used a well-established temporal discounting paradigm and functional MRI (fMRI) to examine engagement of the striatum—including the caudate, putamen, and ventral striatum (VS)—in early adolescence (13–15 years; N=27). Analyses provided evidence of enhanced activity in the caudate and VS during impulsive choice. Exploratory analyses revealed that trait impulsivity was associated with heightened putamen activity during impulsive choices. A more nuanced pattern was evident in the cortex, with the dorsolateral prefrontal cortex mirroring the putamen and posterior parietal cortex showing the reverse association. Taken together, these observations provide an important first glimpse at the distributed neural systems underlying economic choice and trait-like individual differences in impulsivity in the early years of adolescence, setting the stage for prospective-longitudinal and intervention research.en_US
dc.description.sponsorshipNIH R00DA038589en_US
dc.description.sponsorshipNIH DA040717en_US
dc.description.sponsorshipNIH MH107444en_US
dc.rights© 2020 Published by Elsevier Ltd.en_US
dc.titleStriatal bases of temporal discounting in early adolescentsen_US
kusw.kuauthorLejuez, Carl W.
kusw.kudepartmentCofrin Logan Center for Addiction Research and Treatmenten_US
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US

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© 2020 Published by Elsevier Ltd.
Except where otherwise noted, this item's license is described as: © 2020 Published by Elsevier Ltd.