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dc.contributor.authorEshghi, Marziye
dc.contributor.authorStipancic, Kaila L.
dc.contributor.authorMefferd, Antje
dc.contributor.authorRong, Panying
dc.contributor.authorBerry, James D.
dc.contributor.authorYunusova, Yana
dc.contributor.authorGreen, Jordan R.
dc.date.accessioned2020-06-12T20:21:30Z
dc.date.available2020-06-12T20:21:30Z
dc.date.issued2019-12-05
dc.identifier.citationEshghi, M., Stipancic, K. L., Mefferd, A., Rong, P., Berry, J. D., Yunusova, Y., & Green, J. R. (2019). Assessing Oromotor Capacity in ALS: The Effect of a Fixed-Target Task on Lip Biomechanics. Frontiers in neurology, 10, 1288. https://doi.org/10.3389/fneur.2019.01288en_US
dc.identifier.urihttp://hdl.handle.net/1808/30465
dc.descriptionThis work is licensed under a Creative Commons Attribution 4.0 International License.en_US
dc.description.abstractAlternating motion rate (AMR) is a standard measure often included in neurological examinations to assess orofacial neuromuscular integrity. AMR is typically derived from recordings of patients producing repetitions of a single syllable as fast and clear as possible on one breath. Because the task places high demands on oromotor performance, particularly articulatory speed, AMRs are widely considered to be tests of maximum performance and, therefore, likely to reveal underlying neurologic deficits. Despite decades of widespread use, biomechanical studies have shown that speakers often circumvent the presumed speed challenge of the standard AMR task. Specifically, speakers are likely to manipulate their displacements (movement amplitude) instead of speed because this strategy requires less motor effort. The current study examined the effectiveness of a novel fixed-target paradigm for minimizing the truncation of articulatory excursions and maximizing motor effort. We compared the standard AMR task to that of a fixed-target AMR task and focused specifically on the tasks' potential to detect decrements in lip motor performance in persons with dysarthria due to amyotrophic lateral sclerosis (ALS). Our participants were 14 healthy controls and 17 individuals with ALS. For the standard AMR task, participants were instructed to produce the syllable /bα/ as quickly and accurately as possible on one breath. For the fixed-target AMR task, participants were given the same instructions, but were also required to strike a physical target placed under the jaw during the opening phase of each syllable. Lip kinematic data were obtained using 3D electromagnetic articulography. 16 kinematic features were extracted using an algorithmic approach. Findings revealed that compared to the standard task, the fixed-target AMR task placed increased motor demands on the oromotor system by eliciting larger excursions, faster speeds, and greater spatiotemporal variability. In addition, participants with ALS exhibited limited ability to adapt to the higher articulatory demands of the fixed-target task. Between the two AMR tasks, the maximum speed during the fixed-target task showed a moderate association with the ALSFRS-R bulbar subscore. Employment of both standard and fixed-target AMR tasks is, however, needed for comprehensive assessment of oromotor function and for elucidating profiles of task adaptation.en_US
dc.publisherFrontiers Mediaen_US
dc.rights© 2019 Eshghi, Stipancic, Mefferd, Rong, Berry, Yunusova and Green.en_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.subjectAlternating motion rateen_US
dc.subjectFixed-target tasksen_US
dc.subjectAmyotrophic lateral sclerosisen_US
dc.subjectSpeech kinematicsen_US
dc.subjectMaximum performanceen_US
dc.titleAssessing Oromotor Capacity in ALS: The Effect of a Fixed-Target Task on Lip Biomechanicsen_US
dc.typeArticleen_US
kusw.kuauthorRong, Panying
kusw.kudepartmentSpeech-Language-Hearing: Sciences and Disordersen_US
kusw.kudepartmentSpeech Science and Disorders Laben_US
dc.identifier.doi10.3389/fneur.2019.01288en_US
kusw.oaversionScholarly/refereed, publisher versionen_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.identifier.pmidPMC6906194en_US
dc.rights.accessrightsopenAccessen_US


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© 2019 Eshghi, Stipancic, Mefferd, Rong, Berry, Yunusova and Green.
Except where otherwise noted, this item's license is described as: © 2019 Eshghi, Stipancic, Mefferd, Rong, Berry, Yunusova and Green.