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A community-based approach to trials of aerobic exercise in aging and Alzheimer’s disease

dc.contributor.authorVidoni, Eric D.
dc.contributor.authorVan Sciver, Angela
dc.contributor.authorJohnson, David K.
dc.contributor.authorHe, Jianghua
dc.contributor.authorHonea, Robyn A.
dc.contributor.authorHaines, Brian
dc.contributor.authorGoodwin, Jami
dc.contributor.authorLaubinger, M. Pat
dc.contributor.authorAnderson, Heather S.
dc.contributor.authorKluding, Patricia M.
dc.contributor.authorDonnelly, Joseph E.
dc.contributor.authorBillinger, Sandra A.
dc.contributor.authorBurns, Jeffrey M.
dc.date.accessioned2017-06-05T16:28:14Z
dc.date.available2017-06-05T16:28:14Z
dc.date.issued2012
dc.identifier.citationVidoni, E. D., Van Sciver, A., Johnson, D. K., He, J., Honea, R., Haines, B., … Burns, J. M. (2012). A community-based approach to trials of aerobic exercise in aging and Alzheimer’s disease. Contemporary Clinical Trials, 33(6), 1105–1116. http://doi.org/10.1016/j.cct.2012.08.002en_US
dc.identifier.urihttp://hdl.handle.net/1808/24365
dc.description.abstractThe benefits of exercise for aging have received considerable attention in both the popular and academic press. The putative benefits of exercise for maximizing cognitive function and supporting brain health have great potential for combating Alzheimer’s disease (AD). Aerobic exercise offers a low-cost, low-risk intervention that is widely available and may have disease modifying effects. Demonstrating aerobic exercise alters the AD process would have enormous public health implications. The purpose of this paper is to a report the protocol of a current, community-based pilot study of aerobic exercise for AD to guide future investigation. This manuscript provides 1) an overview of possible benefits of exercise in those with dementia, 2) a rationale and recommendations for implementation of a community-based approach, 3) recommendation for implementation of similar study protocols, 4) unique challenges in conducting an exercise trial in AD.en_US
dc.publisherElsevieren_US
dc.rightsThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.subjectRandomized controlled trialen_US
dc.subjectDementiaen_US
dc.subjectPublic-private partnershipen_US
dc.titleA community-based approach to trials of aerobic exercise in aging and Alzheimer’s diseaseen_US
dc.typeArticleen_US
kusw.kuauthorJohnson, David K.
kusw.kudepartmentPsychologyen_US
dc.identifier.doi10.1016/j.cct.2012.08.002
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.identifier.pmidPMC3468654en_US
dc.rights.accessrightsopenAccess


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This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Except where otherwise noted, this item's license is described as: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.