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Chemical Methods for the Synthesis and Modification of Neoclerodane Diterpenes

dc.contributor.authorLozama, Anthony
dc.contributor.authorPrisinzano, Thomas E.
dc.date.accessioned2017-05-03T19:39:17Z
dc.date.available2017-05-03T19:39:17Z
dc.date.issued2009-09-15
dc.identifier.citationLozama, A., & Prisinzano, T. E. (2009). Chemical Methods for the Synthesis and Modification of Neoclerodane Diterpenes. Bioorganic & Medicinal Chemistry Letters, 19(18), 5490–5495. http://doi.org/10.1016/j.bmcl.2009.07.069en_US
dc.identifier.urihttp://hdl.handle.net/1808/23879
dc.description.abstractDiterpenes are a structural class of molecules that are derived from four isoprene subunits and are widespread throughout nature. A number of neoclerodane diterpenes have been found to have biological activity but a limited number of chemical investigations have been conducted. Recently, the neoclerodane diterpene, salvinorin A (12) has been investigated due to its unique pharmacological profile. This review will discuss the chemical methods used to chemically modify and synthesize 12.en_US
dc.publisherElsevieren_US
dc.rightsThis work is made available under an Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0) License.en_US
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/en_US
dc.subjectDiterpeneen_US
dc.subjectNeoclerodaneen_US
dc.subjectSalvinorin Aen_US
dc.subjectSalvia divinorumen_US
dc.titleChemical Methods for the Synthesis and Modification of Neoclerodane Diterpenesen_US
dc.typeArticleen_US
kusw.kuauthorPrisinzano, Thomas E.
kusw.kudepartmentMedicinal Chemistryen_US
dc.identifier.doi10.1016/j.bmcl.2009.07.069en_US
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.identifier.pmidPMC2977960en_US
dc.rights.accessrightsopenAccess


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This work is made available under an Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0) License.
Except where otherwise noted, this item's license is described as: This work is made available under an Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0) License.