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More than two decades of Apc modeling in rodents

dc.contributor.authorZeineldin, Maged
dc.contributor.authorNeufeld, Kristi L.
dc.date.accessioned2017-02-15T17:57:47Z
dc.date.available2017-02-15T17:57:47Z
dc.date.issued2013-01-17
dc.identifier.citationZeineldin, M., & Neufeld, K. L. (2013). More than two decades of Apc modeling in rodents. Biochimica et Biophysica Acta (BBA)-Reviews on Cancer, 1836(1), 80-89.en_US
dc.identifier.urihttp://hdl.handle.net/1808/23178
dc.description.abstractMutation of tumor suppressor gene adenomatous polyposis coli (APC) is an initiating step in most colon cancers. This review summarizes Apc models in mice and rats, with particular concentration on those most recently developed, phenotypic variation among different models, and genotype/phenotype correlations.en_US
dc.publisherElsevieren_US
dc.rightsThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 3.0 (CC BY-NC-ND 3.0 US), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectAdenomatous polyposis coli/APCen_US
dc.subjectApc mouse modelen_US
dc.subjectFAP modelen_US
dc.subjectConditional Apc mutationen_US
dc.subjectIntestinal polyposisen_US
dc.subjectLOH/Apc mouse modelen_US
dc.titleMore than two decades of Apc modeling in rodentsen_US
dc.typeArticleen_US
kusw.kuauthorZeinelden, Maged
kusw.kuauthorNeufeld, Kristi L.
kusw.kudepartmentMolecular Biosciencesen_US
dc.identifier.doi10.1016/j.bbcan.2013.01.001en_US
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.rights.accessrightsopenAccess


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This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 3.0 (CC BY-NC-ND 3.0 US), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Except where otherwise noted, this item's license is described as: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 3.0 (CC BY-NC-ND 3.0 US), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.