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A novel polythyleneimine-coated adeno-associated virus-like particle formulation for efficient siRNA delivery in breast cancer therapy: preparation and in vitro analysis

dc.contributor.authorShao, Wei
dc.contributor.authorPaul, Arghya
dc.contributor.authorChahal, Parminder S.
dc.contributor.authorMena, Jimmy A.
dc.contributor.authorMontes, Johnny
dc.contributor.authorKamen, Amine
dc.contributor.authorPrakash, Satya
dc.date.accessioned2016-07-18T16:50:03Z
dc.date.available2016-07-18T16:50:03Z
dc.date.issued2012-03-22
dc.identifier.citationShao, Wei, Arghya Paul, Sana Abbasi, Parminder S. Chahal, Jimmy A. Mena, Johnny Montes, Amine Kamen, and Satya Prakash. "A Novel Polyethyleneimine-coated Adenoassociated Virus-like Particle Formulation for Efficient SiRNA Delivery in Breast Cancer Therapy: Preparation and in Vitro Analysis." International Journal of Nanomedicine 7 (2012)en_US
dc.identifier.urihttp://hdl.handle.net/1808/21125
dc.description.abstractSystemic delivery of small interfering RNA (siRNA) is limited by its poor stability and limited cell-penetrating properties. To overcome these limitations, we designed an efficient siRNA delivery system using polyethyleneimine-coated virus-like particles derived from adeno-associated virus type 2 (PEI-AAV2-VLPs).en_US
dc.publisherDove Medical Pressen_US
dc.rightsThis work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/
dc.subjectAdeno-asscoiated virus type 2en_US
dc.subjectVirus-like particlesen_US
dc.subjectSmall interfering RNA deliveryen_US
dc.subjectBreast cancer therapyen_US
dc.subjectNanomedicineen_US
dc.titleA novel polythyleneimine-coated adeno-associated virus-like particle formulation for efficient siRNA delivery in breast cancer therapy: preparation and in vitro analysisen_US
dc.typeArticleen_US
kusw.kuauthorPaul, Arghya
dc.identifier.doi10.2147/IJN.S26891en_US
kusw.oaversionScholarly/refereed, publisher versionen_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.rights.accessrightsopenAccess


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This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
Except where otherwise noted, this item's license is described as: This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.