The role of retinoic acid in hepatic lipid homeostasis defined by genomic binding and transcriptome profiling
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The Role of the G-Protein Coupled Receptor C-C Chemokine Receptor 7 in T Lymphocyte Migration and Breast Cancer Metastasis Shannon, Laura Ann (University of Kansas, 2010-08-23)C-C Chemokine Receptor 7 (CCR7) promotes migration of T lymphocytes into and throughout lymph nodes via ligands CCL21 and CCL19. The mechanisms by which CCR7 directs T lymphocyte trafficking are unknown. Using migration ...
Characterization of the functional heterologous desensitization of hypothalamic 5-HT1A receptors after 5-HT2A receptor activation Zhang, Yahong; D'Souza, Deborah N.; Raap, Danı́ K.; Garcia, Francisca; Battaglia, George; Muma, Nancy A.; Van de Kar, Louis D. (Society for Neuroscience, 2001-10-15)Desensitization of 5-HT1A receptors could be involved in the long-term therapeutic effect of anxiolytic and antidepressant drugs. Pretreatment of rats with the 5-HT2A/2C agonist DOI induces an attenuation of hypothalamic ...
T cell receptor alpha-chain gene rearrangements in B-precursor leukemia are in contrast to the findings in T cell acute lymphoblastic leukemia. Comparative study of T cell receptor gene rearrangement in childhood leukemia. Hara, Junichi; Benedict, Stephen H.; Mak, Tak W.; Gelfand, Erwin W. (The American Society for Clinical Investigation, 1987-12)We have analyzed T cell receptor alpha-chain gene configuration using three genomic joining (J) region probes in 64 children with acute lymphoblastic leukemia (ALL). 11 out of 18 T-ALLs were T3 positive; alpha-chain gene ...