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Depression during exacerbations in multiple sclerosis: the importance of uncertainty
Kroencke, Dawn C. Denney, Douglas R. Lynch, Sharon G.
Kroencke, Dawn C.
Denney, Douglas R.
Lynch, Sharon G.
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Abstract
The following correlates of depression were examined in a sample of 166 patients with clinically definite relapsing-remitting (n=140) or secondary progressive (n=26) multiple sclerosis: (a) the present state of the patients' illness (i.e., whether or not they were currently experiencing an exacerbation of their symptoms); (b) their level of uncertainty concerning their illness, and (c) their strategies for coping with their illness. A current exacerbation in symptoms, greater uncertainty of illness, and greater use of emotion-centered forms of coping were all related to depression. Multivariate analyses revealed that uncertainty of illness played a pivotal role as a mediating variable. Exacerbations in illness appeared to heighten patients' levels of uncertainty, and it was largely through this heightened uncertainty that the increases in depression came about
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Date
2001-08
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ARNOLD, HODDER HEADLINE PLC
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Keywords
CLINICAL NEUROLOGY, exacerbations, multiple sclerosis, depression, coping, uncertainty
Citation
Kroencke, DC; Denney, DR; Lynch, SG. Depression during exacerbations in multiple sclerosis: the importance of uncertainty. MULTIPLE SCLEROSIS. Aug 2001. 7(4) : 237-242.