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Quantification of human bocavirus in lower respiratory tract infections in China
Feng Lin Aiping Zeng Ningmin Yang Haiyan Lin En Yang Shengqi Wang David Pintel Jianming Qiu
Feng Lin
Aiping Zeng
Ningmin Yang
Haiyan Lin
En Yang
Shengqi Wang
David Pintel
Jianming Qiu
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Abstract
A quantitative PCR method was established to quantify human bocavirus (HBoV) genomic copies in clinical specimens from children with lower respiratory tract infections (LRTI) in China. A total of 257 respiratory tract specimens were tested, and 7 (2.7%) of these (all sputum samples) were positive, with genomic copies that ranged from 8.0 × 103 to 8.0 × 109 in the samples. The main clinical symptom of patients who were positive for HBoV DNA was a pneumonia-like syndrome represented by high fever and cough. Our results suggest that HBoV may be an important etiological agent of LRTI in children in China.
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2007-06-28
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BioMedCentral
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1750-9378-2-3.pdf
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Feng Lin;Aiping Zeng;Ningmin Yang;Haiyan Lin;En Yang;Shengqi Wang;David Pintel;Jianming Qiu: Quantification of human bocavirus in lower respiratory tract infections in China. Infectious Agents and Cancer 2007, 2(1):3.