Loading...
Effect of Psychosocial Factors on Health Outcomes in Autologous BMT Patients
Ogborn, Valerie
Ogborn, Valerie
Citations
Altmetric:
Abstract
Psychosocial factors have been shown to be indicative of health recovery in cancer populations. However, less is known about Blood and Marrow Transplant (BMT) patients. This paper explores pre-transplant psychosocial factors that may predict poorer health outcomes following autologous transplant (AuBMTs) in patients with hematological malignancies. Participants included 130 cancer patients (51.5% male) who completed a pre-AuBMT evaluation (M = 58.39, SD = 11.71, range = 21 – 80). Data extracted include information regarding measures for distress (DT), problems in daily life (PPL), depressive symptoms (CES-D) and physical and mental health quality of life (PCS-12 and MCS-12). Health outcomes including cancer-related hospital re-admittance, survival rates, and number of medications prescribed within 12 months post-transplant were also extracted. Results indicated that medications were positively correlated to PPL score, r(128) = 0.179, p < 0.05, and to CES-D scores, r(128) = 0.220, p < 0.05, and inversely related to PCS-12 scores, r(128) = -0.293, p < 0.01. ANOVA and Welch ANOVAs indicated insurance status has a significant effect on mortality rate, depression, and physical and health-related quality of life (p<.05). A stepwise multiple linear regression model indicated that approximately 7.9% of the variance of the number of medications used was accounted for by PCS-12. Results suggest that individuals with greater overall problems and depressive symptoms and a poorer physical health quality of life (QOL) were prescribed more medications. Additionally, physical health QOL proved to be a significant predictor for medication use. The impact of insurance status on these outcomes is an area for further exploration. This research supports a relationship between psychosocial variables and health outcomes for BMT patients with a hematological malignancy and may help inform appropriate psychosocial screening and intervention practices for this population.
Description
Date
2016-08-31
Journal Title
Journal ISSN
Volume Title
Publisher
University of Kansas
Research Projects
Organizational Units
Journal Issue
Keywords
Psychology, Bone Marrow Transplant, Depression, Distress, Health Psychology, Psychosocial, Quality of Life