Loading...
Chemical Methods for the Synthesis and Modification of Neoclerodane Diterpenes
Lozama, Anthony Prisinzano, Thomas E.
Lozama, Anthony
Prisinzano, Thomas E.
Citations
Altmetric:
Abstract
Diterpenes are a structural class of molecules that are derived from four isoprene subunits and are
widespread throughout nature. A number of neoclerodane diterpenes have been found to have
biological activity but a limited number of chemical investigations have been conducted. Recently,
the neoclerodane diterpene, salvinorin A (12) has been investigated due to its unique pharmacological
profile. This review will discuss the chemical methods used to chemically modify and synthesize
12.
Description
Date
2009-09-15
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Collections
Research Projects
Organizational Units
Journal Issue
Keywords
Diterpene, Neoclerodane, Salvinorin A, Salvia divinorum
Citation
Lozama, A., & Prisinzano, T. E. (2009). Chemical Methods for the Synthesis and Modification of Neoclerodane Diterpenes. Bioorganic & Medicinal Chemistry Letters, 19(18), 5490–5495. http://doi.org/10.1016/j.bmcl.2009.07.069