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Diet-induced metabolic hamster model of nonalcoholic fatty liver disease

Paul, Arghya
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Abstract
Obesity, hypercholesterolemia, elevated triglycerides, and type 2 diabetes are major risk factors for metabolic syndrome. Hamsters, unlike rats or mice, respond well to diet-induced obesity, increase body mass and adiposity on group housing, and increase food intake due to social confrontation-induced stress. They have a cardiovascular and hepatic system similar to that of humans, and can thus be a useful model for human pathophysiology.
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Date
2011-06-03
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Dove Medical Press
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Chemical & Petroleum Engineering Scholarly Works
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Keywords
Fatty liver disease, In vivo model, Diet, Atherogenic index, Obesity
Citation
Prakash, Satya, Jasmine Bhathena, Aleksandra Urbanska, Arun Kulamarva, Meenakshi Malhotra, Christopher Martoni, and Arghya Paul. "Diet-induced Metabolic Hamster Model of Nonalcoholic Fatty Liver Disease." Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy DMSO (2011): 195. http://dx.doi.org/10.2147/DMSO.S18435
URI
https://hdl.handle.net/1808/18855
DOI
10.2147/DMSO.S18435
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