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Turmeric inhibits parathyroid hormone-related protein (PTHrP) secretion from human rheumatoid synoviocytes
Frye, Jennifer B. Timmermann, Barbara N. Funk, Janet L.
Frye, Jennifer B.
Timmermann, Barbara N.
Funk, Janet L.
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Abstract
Excessive production of parathyroid hormone-related protein (PTHrP) by tumor-like synoviocytes contributes to joint destruction in rheumatoid arthritis (RA). Having previously demonstrated that curcuminoid-only and essential oil-only fractions of turmeric prevent joint destruction in an animal model of RA, we hypothesized that synoviocyte PTHrP production could be one signaling pathway targeted by turmeric (Curcuma longa L.) in RA.
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Date
2012-06-12
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Publisher
BioMed Central
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Keywords
Turmeric, Human rheumatoid synoviocytes, Pthrp secretion
Citation
Frye, J, B Timmermann, and J Funk. 2012. “P01.55. Turmeric Inhibits Parathyroid Hormone-Related Protein (PTHrP) Secretion from Human Rheumatoid Synoviocytes.” BMC Complementary and Alternative Medicine 12 (Suppl 1): P55. http://dx.doi.org/10.1186/1472-6882-12-S1-P55.