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Bubble dynamics and size distributions during focused ultrasound insonation
Yang, Xinmai Roy, Ronald A. Holt, R. Glynn
Yang, Xinmai
Roy, Ronald A.
Holt, R. Glynn
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Abstract
The deposition of ultrasonic energy in tissue can cause tissue damage due to local heating. For pressures above a critical threshold, cavitation will occur, inducing a much larger thermal energy deposition in a local region. The present work develops a nonlinear bubble dynamicsmodel to numerically investigate bubble oscillations and bubble-enhanced heating during focused ultrasound (HIFU) insonation. The model is applied to calculate two threshold-dependent phenomena occurring for nonlinearly oscillating bubbles: Shape instability and growth by rectified diffusion. These instabilities in turn are shown to place physical boundaries on the time-dependent bubble size distribution, and thus the thermal energy deposition.
Description
This is the published version. Copyright © 2004 Acoustical Society of America
Date
2004
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Acoustical Society of America
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This item contains archived web content.
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Keywords
Bubble dynamics, Ultrasonics, Cavitation, Diffusion, Numerical modeling
Citation
Yang, Xinmai, Ronald A. Roy, and R. Glynn Holt. "Bubble Dynamics and Size Distributions during Focused Ultrasound Insonation." The Journal of the Acoustical Society of America J. Acoust. Soc. Am. 116.6 (2004): 3423. http://dx.doi.org/10.1121/1.1823251