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Active Interfacial Shear Microrheology of Aging Protein Films
Dhar, Prajnaparamita Cao, Yanyan Fischer, Thomas M. Zasadzinski, Joseph A.
Dhar, Prajnaparamita
Cao, Yanyan
Fischer, Thomas M.
Zasadzinski, Joseph A.
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Abstract
The magnetically driven rotation of 300 nm diameter rods shows the surface viscosity of albumin at an air-water interface increases from 10−9 to 10−5 N s/m over 2 h while the surface pressure saturates in minutes. The increase in surface viscosity is not accompanied by a corresponding increase in elasticity, suggesting that the protein film anneals with time, resulting in a more densely packed film leading to increased resistance to shear. The nanometer dimensions of the rods provide the same sensitivity as passive microrheology with an improved ability to measure more viscous films.
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This is the published version. Copyright 2010 The American Physical Society
Date
2010-01-04
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American Physical Society
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Dhar, Prajnaparamita, Yanyan Cao, Thomas M. Fischer, and J. A. Zasadzinski. "Active Interfacial Shear Microrheology of Aging Protein Films." Phys. Rev. Lett. Physical Review Letters 104.1 (2010). http://dx.doi.org/10.1103/PhysRevLett.104.016001