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Synthesis of a quinolone library from ynones
Ward, Timothy R. Turunen, Brandon J. Haack, Torsten Neuenswander, Benjamin Shadrick, William R. Georg, Gunda I.
Ward, Timothy R.
Turunen, Brandon J.
Haack, Torsten
Neuenswander, Benjamin
Shadrick, William R.
Georg, Gunda I.
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Abstract
A library of 72 quinolones was synthesized from substituted anthranilic acids, using ynone intermediates. These masked β-dicarbonyl synthons allowed cyclization under milder conditions than previously reported quinolone syntheses.
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2009-11-25
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Elsevier
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Ward, Timothy R. et al. “Synthesis of a Quinolone Library from Ynones.” Tetrahedron letters 50.47 (2009): 6494–9497.