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Spiro-condensation of 5-methoxycarbonyl-1Hpyrrole-2,3-diones with cyclic enoles to form spiro substituted furo[3,2-c]-coumarins and quinolines
Dudovtsev, Alexey Yu Silaichev, Pavel S. Nazarov, Mikhail A. Dmitriev, Maksim V. Maslivets, Andrey N. Rubin, Michael
Dudovtsev, Alexey Yu
Silaichev, Pavel S.
Nazarov, Mikhail A.
Dmitriev, Maksim V.
Maslivets, Andrey N.
Rubin, Michael
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Abstract
Highly efficient spiro-condensation enabling cyclic enoles to act as 1,3-bis-nucleophiles in reaction with pyrrole-2,3-diones acting as 1,2-bis-electrophiles was developed. The corresponding furo[3,2-c]coumarins and furo[3,2-c]quinolines containing a spiro pyrrole fragment were obtained in high yields.
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2016-09-02
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Royal Society of Chemistry
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Dubovtsev, A. Y., Silaichev, P. S., Nazarov, M. A., Dmitriev, M. V., Maslivets, A. N., & Rubin, M. (2016). Spiro-condensation of 5-methoxycarbonyl-1H-pyrrole-2,3-diones with cyclic enoles to form spiro substituted furo[3,2-c]-coumarins and quinolines. RSC Advances, 6(88), 84730-84737. doi:10.1039/c6ra16889b