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Tailoring biomaterial surface properties to modulate host-implant interactions: implication in cardiovascular and bone therapy
Pacelli, Settimio Manoharan, Vijayan Desalvo, Anna Lomis, Nikita Jodha, Kartikeya Singh Prakash, Satya Paul, Arghya
Pacelli, Settimio
Manoharan, Vijayan
Desalvo, Anna
Lomis, Nikita
Jodha, Kartikeya Singh
Prakash, Satya
Paul, Arghya
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Abstract
Host body response to a foreign medical device plays a critical role in defining its fate post implantation. It is thus important to control host-material interactions by designing innovative implant surfaces. In the recent years, biochemical and topographical features have been explored as main target to produce this new type of bioinert or bioresponsive implants. The review discusses specific biofunctional materials and strategies to achieve a precise control over implant surface properties and presents possible solutions to develop next generation of implants, particularly in the fields of bone and cardiovascular therapy.
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2015-10-16
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Royal Society of Chemistry
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Pacelli, Settimio, Vijayan Manoharan, Anna Desalvo, Nikita Lomis, Kartikeya Singh Jodha, Satya Prakash, and Arghya Paul. "Tailoring Biomaterial Surface Properties to Modulate Host-implant Interactions: Implication in Cardiovascular and Bone Therapy." J. Mater. Chem. B 4.9 (2016): 1586-599.