Loading...
Crystallization and preliminary X-ray diffraction studies of d(ACGTAGCTACGT)2:[actinomycin D, (echinomycin)2] and d(ACGTAGCTACGT)2: [actinomycin D, (triostin A)2] complexes
Takusagawa, Hana L. Takusagawa, Fusao
Takusagawa, Hana L.
Takusagawa, Fusao
Citations
Altmetric:
Abstract
A DNA-multiple drug complex, d(ACGTAGCTACGT)2:[actinomycin D, (echinomycin)2] has been crystallized. The crystals belong to the monoclinic space group C2, with unit-cell parameters a = 85.6, b = 72.8, c = 56.6 Å, [beta] = 101.5° at 93 K and Z = 8. The crystal diffracted to 3.0 Å resolution along the DNA fiber axis and to 3.5 Å resolution in other directions. The Patterson maps indicate that all complexes in the crystal are oriented along their helical axes in the [10\bar 1] direction.
Description
This is the publisher's version, also available electronically from http://scripts.iucr.org/cgi-bin/paper?S0907444999016790.
Date
2000-01-01
Journal Title
Journal ISSN
Volume Title
Publisher
International Union of Crystallography
Collections
Files
Research Projects
Organizational Units
Journal Issue
Keywords
DNA-drug complexes, d(ACGTAGCTACGT)2, actimonycin, echinomycin, triostin A.
Citation
Takusagawa, Hana L.; Takusagawa, Fusao. (2000). "Crystallization and preliminary X-ray diffraction studies of d(ACGTAGCTACGT)2:[actinomycin D, (echinomycin)2] and d(ACGTAGCTACGT)2: [actinomycin D, (triostin A)2] complexes." Acta Crystallographica D, 56(3):344-347. http://www.dx.doi.org/10.1107/S0907444999016790.