Loading...
Multiplex DNA Typing of Short-Tandem-Repeat Loci on the Y Chromosome
Redd, Alan J. Clifford, Stephanie L. Stoneking, Mark
Redd, Alan J.
Clifford, Stephanie L.
Stoneking, Mark
Citations
Altmetric:
Abstract
To facilitate evolutionary and forensic studies of DNA
polymorphisms on the Y chromosome, we devised a
multiplex amplification procedure for short-tandemrepeat
(STR) loci. Four tetranucleotide STR loci
(DYS19, DYS390, DYS391, and DYS393) were simultaneously
amplified with FAM-labeled primers and
genotypes were determined with an automated DNA
sequencer. We typed 162 males from three U.S. populations
(African-Americans, European-Americans and
Hispanics) and found that the haplotype diversities
range from 0.920 to 0.969. This quadruplex system
provides a facile means of genotyping these Y chromosome
STRs, and should be useful in population
genetic and forensic applications.
Description
This is the published version. Copyright 1997 de Gruyter.
Date
1997-08
Journal Title
Journal ISSN
Volume Title
Publisher
De Gruyter
Collections
Files
Loading...
redd_bc_v378n8.pdf
Adobe PDF, 8.75 MB
Research Projects
Organizational Units
Journal Issue
Keywords
Citation
Redd, Alan J., Stephanie L. Clifford, and Mark Stoneking. "Multiplex DNA Typing of Short-tandem-repeat Loci on the Y Chromosome." Biological Chemistry 378.8 (1997): 923-27.