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How to Resolve an Ethical Dilemma Concerning Randomized Clinical Trials

Marquis, Don
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Abstract
An apparent ethical dilemma arises when physicians consider enrolling their patients in randomized clinical trials. Suppose that a randomized clinical trial comparing two treatments is in progress, and a physician has an opinion about which treatment is better. The physician has a duty to promote the patient's best medical interests and therefore seems to be obliged to advise the patient to receive the treatment that the physician prefers. This duty creates a barrier to the enrollment of patients in randomized clinical trials.1-10 Two strategies are often used to resolve the dilemma in favor of enrolling patients in clinical trials.
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1999-08-26
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Massachusetts Medical Society
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Marquis, Don. "How to Resolve an Ethical Dilemma Concerning Randomized Clinical Trials." The New England Journal of Medicine Volume 341 Number 9 691-3. http://www.dx.doi.org/10.1056/NEJM199908263410912
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