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Prenatal DHA Supplementation and Infant Attention

Colombo, John
Gustafson, Kathleen M.
Gajewski, Byron J.
Shaddy, D. Jill
Kerling, Elizabeth Helen
Thodosoff, Jocelynn M.
Doty, Tasha
Brez, Caitlin C.
Carlson, Susan E.
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Abstract
Background Results of randomized trials on the effects of prenatal docosahexaenoic acid (DHA) on infant cognition are mixed, but most trials have used global standardized outcomes, which may not be sensitive to effects of DHA on specific cognitive domains. Methods Women were randomized to 600 mg/d DHA or a placebo for the last two trimesters of pregnancy. Infants of these mothers were then followed on tests of visual habituation at 4, 6, and 9 months of age. Results DHA supplementation did not affect look duration or habituation parameters but infants of supplemented mothers maintained high levels of sustained attention (SA) across the first year; SA declined for the placebo group. The supplemented group also showed significantly reduced attrition on habituation tasks, especially at 6 and 9 months. Conclusion The findings support with the suggestion that prenatal DHA may positively affect infants’ attention and regulation of state.
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2016-06-30
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Nature Publishing Group
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Colombo, John et al. “Prenatal DHA Supplementation and Infant Attention.” Pediatric research 80.5 (2016): 656–662.
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