Loading...
Thumbnail Image
Publication

Phylogenetic assessment of filoviruses: how many lineages of Marburg virus?

Peterson, A. Townsend
Holder, Mark T.
Citations
Altmetric:
Abstract
Filoviruses have to date been considered as consisting of one diverse genus (Ebola viruses) and one undifferentiated genus (Marburg virus). We reconsider this idea by means of detailed phylogenetic analyses of sequence data available for the Filoviridae: using coalescent simulations, we ascertain that two Marburg isolates (termed the “RAVN” strain) represent a quite-distinct lineage that should be considered in studies of biogeography and host associations, and may merit recognition at the level of species. In contrast, filovirus isolates recently obtained from bat tissues are not distinct from previously known strains, and should be considered as drawn from the same population. Implications for understanding the transmission geography and host associations of these viruses are discussed.
Description
This is the publisher's version, also available electronically from http://onlinelibrary.wiley.com.
Date
2012-07-01
Journal Title
Journal ISSN
Volume Title
Publisher
Wiley Open Access
Research Projects
Organizational Units
Journal Issue
Keywords
Ebola virus, Filovirus, Lineage identity, Marburg virus
Citation
Peterson, A. Townsend; Holder, Mark T. Phylogenetic assessment of filoviruses: how many lineages of Marburg virus? 2012. Ecology and Evolution 2(8):1826-1833. http://dx.doi.org/10.1002/ece3.297
Embedded videos