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Synthesis of a Library of 1,5,2-Dithiazepine 1,1-Dioxides. Part 2: Routes to Bicyclic Sultams
Zang, Qin ; Javed, Salim ; Zhou, Aihua ; Knudtson, Christopher Anton ; Bi, Danse ; Basha, Fatima Z. ; Hanson, Paul R.
Zang, Qin
Javed, Salim
Zhou, Aihua
Knudtson, Christopher Anton
Bi, Danse
Basha, Fatima Z.
Hanson, Paul R.
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Abstract
The synthesis of a library of bicyclic sultams incorporating the 1,5,2-dithiazepine 1,1-dioxide moiety is reported. Following scaffold synthesis via a one-pot sulfonylation/intramolecular thia-Michael protocol, several additional cyclization strategies have been realized enabling access to new bicyclic sultams.
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2012-12-31
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Elsevier
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Zang, Q., Javed, S., Zhou, A., Knudtson, C. A., Bi, D., Basha, F. Z., & Hanson, P. R. (2012). Synthesis of a Library of 1,5,2-Dithiazepine 1,1-Dioxides. Part 2: Routes to Bicyclic Sultams. Heterocycles, 86(2), 10.3987/COM–12–S(N)122. http://doi.org/10.3987/COM-12-S(N)122