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Synthesis and bacterial biofilm inhibition studies of ethyl N-(2-phenethyl) carbamate derivatives

Rogers, Steven A.
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Abstract
An 88 member library based upon the marine bacterial metabolite ethyl N-(2-phenethyl) carbamate was evaluated for bacterial biofilm inhibition against a panel of medically relevant strains. These studies culminated in the discovery of a new class of molecules capable of inhibiting the formation of S. aureus biofilms with low micromolar IC50 values.
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This is the published version. Copyright Royal Society of Chemistry
Date
2010-07-08
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Royal Society of Chemistry
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Chemistry Scholarly Works
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Rogers, Steven A., Daniel C. Whitehead, Trey Mullikin, and Christian Melander. "Synthesis and Bacterial Biofilm Inhibition Studies of Ethyl N-(2-phenethyl) Carbamate Derivatives." Organic & Biomolecular Chemistry Org. Biomol. Chem. 8.17 (2010): 3857. DOI:10.1039/C0OB00063A
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https://hdl.handle.net/1808/18970
DOI
10.1039/C0OB00063A
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